Besides, a weakening trend in the Asian region also weighed on the trading sentiments here.
Snapping its five-day long winning streak, the 30-share barometer fell by 54.16 points, or 0.26 per cent, to 21,065.96, mainly due to weakness in PSUs, banking, realty capital goods, auto and metal sector stocks.
Similarly, the National Stock Exchange index Nifty moved down by 14.95 points, or 0.24 per cent, to 6,262.00.
Brokers said besides profit-booking by speculators after recent gains, subdued economic growth data for the December quarter and a weak trend in the Asian markets amid rising tensions over Ukraine, dampened the trading sentiments.
Also, the Indian economy grew below expectations at 4.7 per cent in the October-December quarter.
Besides, decline in February sales posted by auto makers, including Maruti Suzuki, Tata Motors and M&M was another negative factor, brokers added.
Among other Asian markets, Nikkei was trading 1.75 per cent lower while Hong Kong’s Hang Seng index shed 0.71 per cent in early trade today.