The 30-share index fell by 66.06 points, or 0.32 per cent, to 20,539.02, led by losses in stocks of FMCG, IT, banking, realty and oil and gas sectors. The Sensex had gained nearly 388 points in the previous session.
Similarly, the wide-based National Stock Exchange index Nifty shed 17.15 points, or 0.28 per cent, to 6,098.20.
Brokers said profit booking by speculators after yesterday’s gains and a mixed trend in the Asian region mainly influenced the trading sentiment.
In the Asian region, Japan’s Nikkei Index was down by 0.69 per cent, while Hong Kong’s Hang Seng index gained 0.09 per cent in early trade today. The US Dow Jones Industrial Average ended 0.05 per cent higher yesterday.