Stocks of oil & gas, FMCG, capital goods, auto and metal sectors led the fall.
The 30-share index Sensex, which had gained 118.17 points in the previous session, lost 35.58 points, or 0.16 per cent, to 22,840.96 in early trade today.
Similarly, the National Stock Exchange Nifty declined by 4.20 points, or 0.06 per cent, to Rs 6,836.60.
The stock market was closed yesterday for Lok Sabha polls in Mumbai.
Besides profit-booking by speculators amid a weak trend in the other Asian markets mainly influenced the sentiment, brokers said.
Among other Asian markets, Hong Kong’s Hang Seng was down 0.17 per cent while Japan’s Nikkei fell 0.24 per cent in early trade today.